Real Time - oncogenes
News - oncogenes
Cancer may require simpler genetic mutations than previously thought
25 May 2012, 10:01 am
( Harvard Medical School ) Scientists have long known that cancer cells can proliferate by deleting both copies of the tumor suppressor genes that would otherwise kill them. Now research shows they can also grow by deleting single copies of the genes, especially when clusters of those genes appear randomly on a chromosome. The discovery sheds new light on tumorigenesis and explains why large ...
Press Release
22 May 2012, 2:09 am
Mirna Therapeutics Inc. Posted on:22 May 12 Mirna Therapeutics, Inc., a biotechnology company pioneering microRNA replacement therapies for cancer, announced that new preclinical data from its lead therapeutic program will be presented this week at two different conferences: 2012 TIDES Oligonucleotide and Peptide Research, Technology, and Product Development Conference in Las Vegas, Nevada, and ...
Melanoma genome sequencing reveals frequent PREX2 mutations
9 May 2012, 12:23 pm
Melanoma is notable for its metastatic propensity, lethality in the advanced setting and association with ultraviolet exposure early in life. To obtain a comprehensive genomic view of melanoma in humans, we sequenced the genomes of 25 metastatic melanomas and matched germline DNA. A wide range of point mutation rates was observed: lowest in melanomas whose primaries arose on non-ultraviolet ...
Researchers discover CD19 pathway that leads to lymphoma
8 May 2012, 12:42 am
Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain
oncogenes (cancer-causing genes), and the new research may lay the groundwork for breaking that addiction and effectively treating aggressive types of B cell lymphoma.
Protein may represent a switch to turn off B cell lymphoma
7 May 2012, 1:49 pm
( Children's Hospital of Philadelphia ) Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain
oncogenes (cancer-causing genes), and the new research may lay the groundwork for breaking that addiction and effectively treating ...
This Week in Cancer Cell
28 April 2012, 12:03 am
In Cancer Cell this week: targeting non-classic
oncogenes to treat T-ALL, and more. Full-text access for registered users only. Existing users login here . New to GenomeWeb?
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